1XPL
Crystal Structure of Staphylococcus aureus HMG-COA Synthase with Acetoacetyl-COA and Acetylated Cysteine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | 3-hydroxy-3-methylglutaryl CoA synthase | polymer | 396 | 44335.5 | 4 | UniProt (Q79ZY6) | Staphylococcus aureus subsp. aureus | |
| 2 | E, F, H, I, K... (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
| 3 | G, J, M, P (A, B, C, D) | ACETOACETYL-COENZYME A | non-polymer | 851.6 | 4 | Chemie (CAA) | |||
| 4 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 455 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 388 (UniProt: Q79ZY6)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Ala 2 | - | cloning artifact |
| Scy 111 | Cys 111 | microheterogeneity |
| Leu 389 | - | cloning artifact |
| Glu 390 | - | cloning artifact |
| His 391 | - | expression tag |
| His 392 | - | expression tag |
| His 393 | - | expression tag |
| His 394 | - | expression tag |
| His 395 | - | expression tag |
| His 396 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 177341.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 4174.9 | |
| All* | Total formula weight | 181516.9 |
