1XOR
Catalytic Domain Of Human Phosphodiesterase 4D In Complex With Zardaverine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | polymer | 349 | 40096.4 | 2 | UniProt (Q08499) Pfam (PF00233) | Homo sapiens (human) | DPDE3, PDE43 |
| 2 | C, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, G (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | E, H (A, B) | 6-(4-DIFLUOROMETHOXY-3-METHOXY-PHENYL)-2H-PYRIDAZIN-3-ONE | non-polymer | 268.2 | 2 | Chemie (ZAR) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 653 | Chemie (HOH) |
Sequence modifications
A, B: 86 - 413 (UniProt: Q08499)
| PDB | External Database | Details |
|---|---|---|
| Met 65 | - | initiating methionine |
| Gly 66 | - | cloning artifact |
| Ser 67 | - | cloning artifact |
| Ser 68 | - | cloning artifact |
| His 69 | - | expression tag |
| His 70 | - | expression tag |
| His 71 | - | expression tag |
| His 72 | - | expression tag |
| His 73 | - | expression tag |
| His 74 | - | expression tag |
| Ser 75 | - | cloning artifact |
| Ser 76 | - | cloning artifact |
| Gly 77 | - | cloning artifact |
| Leu 78 | - | cloning artifact |
| Val 79 | - | cloning artifact |
| Pro 80 | - | cloning artifact |
| Arg 81 | - | cloning artifact |
| Gly 82 | - | cloning artifact |
| Ser 83 | - | cloning artifact |
| His 84 | - | cloning artifact |
| Met 85 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 80192.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 715.9 | |
| All* | Total formula weight | 80908.6 |
