1XN2
New substrate binding pockets for beta-secretase.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Beta-secretase 1 | polymer | 389 | 43312.8 | 4 | UniProt (P56817) Pfam (PF00026) | Homo sapiens (human) | Beta-site APP cleaving enzyme 1, Beta-site amyloid precursor protein cleaving enzyme 1, Aspartyl protease 2, Asp 2, ASP2, Membrane-associated aspartic protease 2, Memapsin-2 |
| 2 | E, F, G, H (E, F, G, H) | OM03-4 | polymer | 12 | 1638.8 | 4 | |||
| 3 | I, J, K, L, M... (A, B, C, D, E...) | water | water | 18.0 | 723 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 179806.4 | |
| All* | Total formula weight | 179806.4 |
