1XMN
Crystal structure of thrombin bound to heparin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | Thrombin light chain | polymer | 36 | 4096.5 | 4 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (human) | Coagulation factor II |
| 2 | B, D, F, H (B, D, F, H) | Thrombin heavy chain | polymer | 259 | 29780.2 | 4 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (human) | Coagulation factor II |
| 3 | I (I) | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid | branched | 1750.4 | 1 | In PDB GlyTouCan (G82873VJ) | |||
| 4 | J (J) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | K (K) | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose | branched | 1494.2 | 1 | In PDB GlyTouCan (G40789QE) | |||
| 6 | L, M (L, M) | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G07375KG) | |||
| 7 | N (N) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 8 | BA, O, S, W (H, B, D, F) | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide | non-polymer | 454.0 | 4 | BIRD (PRD_000020) Chemie (0G6) | |||
| 9 | CA, P, T, X (H, B, D, F) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 10 | AA, DA, Q, R, U... (F, H, B, D) | GLYCEROL | non-polymer | 92.1 | 8 | Chemie (GOL) | |||
| 11 | EA, FA, GA, HA, IA... (A, B, C, D, E...) | water | water | 18.0 | 750 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 135507.0 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 5428.7 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2644.7 | |
| All* | Total formula weight | 143580.4 |
