1XKB
FACTOR XA COMPLEXED WITH A SYNTHETIC INHIBITOR FX-2212A,(2S)-(3'-AMIDINO-3-BIPHENYLYL)-5-(4-PYRIDYLAMINO)PENTANOIC ACID
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, B) | BLOOD COAGULATION FACTOR XA | polymer | 95 | 10386.5 | 2 | UniProt (P00742) Pfam (PF00008) Pfam (PF14670) | Homo sapiens (human) | STUART FACTOR |
| 2 | B, D (C, D) | BLOOD COAGULATION FACTOR XA | polymer | 235 | 26604.3 | 2 | UniProt (P00742) Pfam (PF00089) | Homo sapiens (human) | STUART FACTOR |
| 3 | E, F, H (A, C, D) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 4 | G, I (C, D) | (2S)-(3'-AMIDINO-3-BIPHENYL)-5-(4-PYRIDYLAMINO)PENTANOIC ACID | non-polymer | 388.5 | 2 | Chemie (4PP) | |||
| 5 | J, K, L, M (A, C, B, D) | water | water | 18.0 | 299 | Chemie (HOH) |
Sequence modifications
A, B: 45 - 139 (UniProt: P00742)
| PDB | External Database | Details |
|---|---|---|
| Bhd 63 | Asp 103 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 73981.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 897.2 | |
| All* | Total formula weight | 74878.8 |
