1XK3
NADPH- and Ascorbate-Supported Heme Oxygenase Reactions are Distinct. Regiospecificity of Heme Cleavage by the R183E Mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Heme oxygenase 1 | polymer | 233 | 26870.5 | 2 | UniProt (P09601) Pfam (PF01126) | Homo sapiens (human) | HO-1 |
| 2 | C, E (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 3 | D (A) | NITRIC OXIDE | non-polymer | 30.0 | 1 | Chemie (NO) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 262 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 233 (UniProt: P09601)
| PDB | External Database | Details |
|---|---|---|
| Glu 183 | Arg 183 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 53741.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1263.0 | |
| All* | Total formula weight | 55004.1 |
