1XIV

Plasmodium falciparum lactate dehydrogenase complexed with 2-({4-chloro-[hydroxy(methoxy)methyl]cyclohexyl}amino)ethane-1,1,2-triol

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	L-lactate dehydrogenase	polymer	323	35055.6	1	UniProt (Q27743) Pfam (PF00056) Pfam (PF02866) In PDB	Plasmodium falciparum (malaria parasite P. falciparum)	LDH-P
2	A	2-({4-CHLORO-2-[HYDROXY(METHOXY)METHYL]CYCLOHEXYL}AMINO)ETHANE-1,1,2-TRIOL	non-polymer		269.7	1	Chemie (RB2)
3	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4		water	water		18.0	360	Chemie (HOH)

Sequence modifications

A: 18 - 332 (UniProt: Q27743)

PDB	External Database	Details
His 330	-	expression tag
Ala 331	-	expression tag
His 332	-	expression tag
His 333	-	expression tag
His 334	-	expression tag
His 335	-	expression tag
His 336	-	expression tag
His 337	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	35055.6
Non-Polymers*	Number of molecules	2
	Total formula weight	361.8
All*	Total formula weight	35417.4

*Water molecules are not included.