1XFZ

Crystal structure of anthrax edema factor (EF) in complex with calmodulin in the presence of 1 millimolar exogenously added calcium chloride

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Calmodulin-sensitive adenylate cyclase	polymer	777	90128.9	6	UniProt (P40136) Pfam (PF07737) Pfam (PF03497) Pfam (PF20850) In PDB	Bacillus anthracis	ATP pyrophosphate-lyase, Adenylyl cyclase, Edema factor, EF, Anthrax edema toxin adenylate cyclase component
2	O, P, Q, R, S...	Calmodulin 2	polymer	149	16851.6	6	UniProt (P62158) Pfam (PF13499) UniProt (by SIFTS) (P0DP23) In PDB	Homo sapiens (human)
3	A, B, C, D, E...	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
4	Q, R, S, T, O...	CALCIUM ION	non-polymer		40.1	18	Chemie (CA)

Sequence modifications

A, B, C, D, E, F: 33 - 800 (UniProt: P40136)

PDB	External Database	Details
Met 24	-	initiating methionine
His 25	-	expression tag
His 26	-	expression tag
His 27	-	expression tag
His 28	-	expression tag
His 29	-	expression tag
His 30	-	expression tag
Ala 31	-	cloning artifact
Ala 32	-	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	641882.8
Non-Polymers*	Number of molecules	24
	Total formula weight	867.2
All*	Total formula weight	642750.0

*Water molecules are not included.