1XFY

Crystal structure of anthrax edema factor (EF) in complex with calmodulin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Calmodulin-sensitive adenylate cyclase	polymer	777	90128.9	6	UniProt (P40136) Pfam (PF07737) Pfam (PF03497) Pfam (PF20850) In PDB	Bacillus anthracis	ATP pyrophosphate-lyase, Adenylyl cyclase, Edema factor, EF, Anthrax edema toxin adenylate cyclase component
2	O, P, Q, R, S...	Calmodulin 2	polymer	149	16851.6	6	UniProt (P62158) Pfam (PF13499) UniProt (by SIFTS) (P0DP23) In PDB	Homo sapiens (human)
3	A, B, C, D, E...	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
4	S, T, O, P, Q...	CALCIUM ION	non-polymer		40.1	12	Chemie (CA)

Sequence modifications

A, B, C, D, E, F: 33 - 800 (UniProt: P40136)

PDB	External Database	Details
Met 24	-	initiating methionine
His 25	-	expression tag
His 26	-	expression tag
His 27	-	expression tag
His 28	-	expression tag
His 29	-	expression tag
His 30	-	expression tag
Ala 31	-	cloning artifact
Ala 32	-	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	641882.8
Non-Polymers*	Number of molecules	18
	Total formula weight	626.8
All*	Total formula weight	642509.5

*Water molecules are not included.