1X9N
Crystal Structure of Human DNA Ligase I bound to 5'-adenylated, nicked DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | dideoxy terminated DNA | polymer | 13 | 3982.6 | 1 | |||
| 2 | B (C) | 5'-phosphorylated DNA | polymer | 15 | 4641.0 | 1 | |||
| 3 | C (D) | template DNA | polymer | 28 | 8529.5 | 1 | |||
| 4 | D (A) | DNA ligase I | polymer | 688 | 76609.3 | 1 | UniProt (P18858) Pfam (PF04675) Pfam (PF01068) Pfam (PF04679) | Homo sapiens (human) | Polydeoxyribonucleotide synthase [ATP] |
| 5 | E (C) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) |
Sequence modifications
A: 233 - 919 (UniProt: P18858)
| PDB | External Database | Details |
|---|---|---|
| Met 232 | - | initiating methionine |
| Mse 308 | Met 308 | modified residue |
| Mse 393 | Met 393 | modified residue |
| Mse 480 | Met 480 | modified residue |
| Mse 501 | Met 501 | modified residue |
| Mse 543 | Met 543 | modified residue |
| Mse 723 | Met 723 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 93762.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 347.2 | |
| All* | Total formula weight | 94109.6 |
