1X8I
Crystal Structure of the Zinc Carbapenemase CphA in Complex with the Antibiotic Biapenem
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase | polymer | 227 | 25163.8 | 1 | UniProt (P26918) Pfam (PF00753) | Aeromonas hydrophila | |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C, D, E, F, G... (A) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 4 | I (A) | 5H-PYRAZOLO(1,2-A)(1,2,4)TRIAZOL-4-IUM, 6-((2-CARBOXY-6-(1-HYDROXYETHYL)-4-METHYL-7-OXO-1-AZABICYCLO(3.2.0)HEPT-2-EN-3-YL)THIO)-6,7-DIHYDRO-, HYDROXIDE, INNER SALT, (4R-(4ALPHA,5BETA,6BETA(R*)))- | non-polymer | 370.4 | 1 | Chemie (BMH) | |||
| 5 | J (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | K (A) | water | water | 18.0 | 188 | Chemie (HOH) |
Sequence modifications
A: 41 - 307 (UniProt: P26918)
| PDB | External Database | Details |
|---|---|---|
| Gly 220 | Asn 192 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25163.8 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1104.3 | |
| All* | Total formula weight | 26268.1 |
