1X71
Crystal structure of Siderocalin (NGAL, Lipocalin 2) complexed with TRENCAM-3,2-HOPO, a cepabactin analogue
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Neutrophil gelatinase-associated lipocalin | polymer | 178 | 20556.4 | 3 | UniProt (P80188) Pfam (PF00061) | Homo sapiens (human) | NGAL, P25, 25 kDa alpha-2-microglobulin-related subunit of MMP-9, Lipocalin 2, Oncogene 24p3 |
| 2 | D, G, J (A, B, C) | FE (III) ION | non-polymer | 55.8 | 3 | Chemie (FE) | |||
| 3 | E, F, H, I, K (A, B, C) | 2,3-DIHYDROXYBENZAMIDE | non-polymer | 153.1 | 5 | Chemie (DB1) | |||
| 4 | L, M, N (A, B, C) | water | water | 18.0 | 116 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 178 (UniProt: P80188)
| PDB | External Database | Details |
|---|---|---|
| Ser 87 | Cys 107 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 61669.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 933.2 | |
| All* | Total formula weight | 62602.5 |
