1WZI
Structural basis for alteration of cofactor specificity of Malate dehydrogenase from Thermus flavus
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Malate dehydrogenase | polymer | 327 | 35460.6 | 2 | UniProt (P10584) | Thermus thermophilus | |
| 2 | C, D (A, B) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 624 | Chemie (HOH) |
Sequence modifications
A, B: 0 - 332 (UniProt: P10584)
| PDB | External Database | Details |
|---|---|---|
| Gly 41 | Glu 42 | engineered mutation |
| Ser 42 | Ile 43 | engineered mutation |
| Glu 43 | Pro 44 | engineered mutation |
| Arg 44 | Gln 45 | engineered mutation |
| Ser 45 | Ala 46 | engineered mutation |
| Phe 46 | Met 47 | engineered mutation |
| Gln 47 | Lys 48 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 70921.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1490.8 | |
| All* | Total formula weight | 72412.1 |
