1WUU

crystal structure of human galactokinase complexed with MgAMPPNP and galactose

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Galactokinase	polymer	399	43641.2	4	UniProt (P51570) Pfam (PF10509) Pfam (PF00288) Pfam (PF08544)	Homo sapiens (human)	Galactose kinase
2	E, H, K, N (A, B, C, D)	alpha-D-galactopyranose	non-polymer		180.2	4	Chemie (GLA)
3	F, I, L, O (A, B, C, D)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
4	G, J, M, P (A, B, C, D)	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	4	Chemie (ANP)
5	Q, R, S, T (A, B, C, D)	water	water		18.0	384	Chemie (HOH)

Sequence modifications

A, B, C, D: 2 - 392 (UniProt: P51570)

PDB	External Database	Details
Mse -6	-	expression tag
Ala -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
Mse 55	Met 55	modified residue
Mse 60	Met 60	modified residue
Mse 180	Met 180	modified residue
Mse 185	Met 185	modified residue
Mse 192	Met 192	modified residue
Mse 307	Met 307	modified residue
Mse 343	Met 343	modified residue
Mse 365	Met 365	modified residue

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	174564.7
Non-Polymers*	Number of molecules	12
	Total formula weight	2842.6
All*	Total formula weight	177407.3

*Water molecules are not included.