1WUT
Acyl Ureas as Human Liver Glycogen Phosphorylase Inhibitors for the Treatment of Type 2 Diabetes
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Glycogen phosphorylase, muscle form | polymer | 842 | 97291.2 | 1 | UniProt (P00489) Pfam (PF00343) In PDB | Oryctolagus cuniculus (rabbit) | Myophosphorylase |
| 2 | A | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 1 | Chemie (PLP) | |||
| 3 | A | 7-[2,6-DICHLORO-4-({[(2-CHLOROBENZOYL)AMINO]CARBONYL}AMINO)PHENOXY]HEPTANOIC ACID | non-polymer | 487.8 | 1 | Chemie (BN2) | |||
| 4 | water | water | 18.0 | 240 | Chemie (HOH) |
Sequence modifications
A: 1 - 842 (UniProt: P00489)
| PDB | External Database | Details |
|---|---|---|
| Ile 380 | Leu 380 | CONFLICT |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 97291.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 734.9 | |
| All* | Total formula weight | 98026.1 |
