1WU1
Factor Xa in complex with the inhibitor 4-[(5-chloroindol-2-yl)sulfonyl]-2-(2-methylpropyl)-1-[[5-(pyridin-4-yl) pyrimidin-2-yl]carbonyl]piperazine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Coagulation factor X, heavy chain | polymer | 233 | 26346.0 | 1 | UniProt (P00742) Pfam (PF00089) | Homo sapiens (human) | Stuart factor, Stuart-Prower factor |
| 2 | B (B) | Coagulation factor X, light chain | polymer | 95 | 10386.5 | 1 | UniProt (P00742) Pfam (PF00008) Pfam (PF14670) | Homo sapiens (human) | Stuart factor, Stuart-Prower factor |
| 3 | C, D (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 4 | E (A) | 5-CHLORO-2-({3-ISOBUTYL-4-[(5-PYRIDIN-4-YLPYRIMIDIN-2-YL)CARBONYL]PIPERAZIN-1-YL}SULFONYL)-1H-INDOLE | non-polymer | 539.0 | 1 | Chemie (D91) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 76 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36732.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 619.2 | |
| All* | Total formula weight | 37351.7 |
