1WT3
Mutant human ABO(H) blood group glycosyltransferase with bound UDP and acceptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histo-blood group ABO system transferase | polymer | 292 | 34137.4 | 1 | UniProt (P16442) Pfam (PF03414) | Homo sapiens (human) | ABO(H) blood group A glycosyltransferase |
| 2 | B (B) | alpha-L-fucopyranose-(1-2)-hexyl beta-D-galactopyranoside | branched | 410.5 | 1 | In PDB GlyTouCan (G40799EF) | |||
| 3 | C, D, E, F (A) | MERCURY (II) ION | non-polymer | 200.6 | 4 | Chemie (HG) | |||
| 4 | G (A) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 1 | Chemie (UDP) | |||
| 5 | H (A) | water | water | 18.0 | 228 | Chemie (HOH) |
Sequence modifications
A: 64 - 354 (UniProt: P16442)
| PDB | External Database | Details |
|---|---|---|
| Met 63 | - | initiating methionine |
| Ser 74 | Pro 74 | engineered mutation |
| Arg 268 | Gly 268 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34137.4 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 410.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1206.5 | |
| All* | Total formula weight | 35754.4 |
