1WS5
Crystal structure of Jacalin-Me-alpha-Mannose complex: Promiscuity vs Specificity
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, G (A, G) | Agglutinin alpha chain | polymer | 133 | 14643.4 | 2 | UniProt (P18670) Pfam (PF01419) | Artocarpus integer | Jacalin alpha chain |
| 2 | B, D, F, H (B, D, F, H) | Agglutinin beta-3 chain | polymer | 20 | 2031.2 | 4 | UniProt (P18673) | Artocarpus integer | Jacalin beta-3 chain |
| 3 | C, E (C, E) | Agglutinin alpha chain | polymer | 133 | 14673.5 | 2 | UniProt (P18670) Pfam (PF01419) | Artocarpus integer | Jacalin alpha chain |
| 4 | I, J, K, L (A, C, E, G) | methyl alpha-D-mannopyranoside | non-polymer | 194.2 | 4 | Chemie (MMA) | |||
| 5 | M, N, O, P, Q... (A, B, C, D, E...) | water | water | 18.0 | 257 | Chemie (HOH) |
Sequence modifications
A, G: 1 - 133 (UniProt: P18670)
B, D, F, H: 1 - 20 (UniProt: P18673)
| PDB | External Database | Details |
|---|---|---|
| Val 45 | Lys 45 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ser 19 | Val 19 | conflict |
| Ala 20 | Ser 20 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 66758.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 776.7 | |
| All* | Total formula weight | 67535.4 |
