1WO4

Solution structure of Minimal Mutant 2 (MM2): Multiple alanine mutant of non-native CHANCE domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	CREB Binding Protein	polymer	25	2404.9	1	UniProt (Q92793) Pfam (PF02135)
2	B (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)

Sequence modifications

A: 1 - 25 (UniProt: Q92793)

PDB	External Database	Details
Ala 1	Glu 376	engineered mutation
Ser 3	Arg 378	engineered mutation
Ala 6	Ser 381	engineered mutation
Ser 8	Pro 383	engineered mutation
Lys 9	His 384	engineered mutation
Ala 11	Arg 386	engineered mutation
Ala 12	Thr 387	engineered mutation
Ala 13	Met 388	engineered mutation
Ala 14	Lys 389	engineered mutation
Ala 17	Leu 392	engineered mutation
Ala 18	Asn 393	engineered mutation
Ala 24	Gln 399	engineered mutation
Lys 25	Ala 400	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	2404.9
Non-Polymers*	Number of molecules	1
	Total formula weight	65.4
All*	Total formula weight	2470.3

*Water molecules are not included.