1WK8
Isoleucyl-tRNA synthetase editing domain complexed with the pre-transfer editing substrate analogue, Val-AMS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Isoleucyl-tRNA synthetase | polymer | 194 | 21619.7 | 2 | UniProt (P56690) Pfam (PF00133) | Thermus thermophilus | Isoleucine--tRNA ligase, IleRS, Fragment |
| 2 | C (B) | 5'O-[N-(L-VALYL)SULPHAMOYL]ADENOSINE | non-polymer | 445.5 | 1 | Chemie (VMS) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 274 | Chemie (HOH) |
Sequence modifications
A, B: 196 - 388 (UniProt: P56690)
| PDB | External Database | Details |
|---|---|---|
| Met 195 | - | initiating methionine |
| Pro 274 | Gln 274 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43239.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 445.5 | |
| All* | Total formula weight | 43684.9 |
