1WCY

Crystal Structure Of Human Dipeptidyl Peptidase IV (DPPIV) Complex With Diprotin A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Dipeptidyl peptidase IV	polymer	740	85880.0	2	UniProt (P27487) Pfam (PF00930) Pfam (PF00326)	Homo sapiens (human)	DPP IV, T-cell activation antigen CD26, TP103, Adenosine deaminase complexing protein-2, ADABP
2	C, D (C, D)	Diprotin A	polymer	3	341.4	2
3	E, I (E, I)	alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		367.3	2	In PDB GlyTouCan (G86851RC)
4	F, G, H, J, K (F, G, H, J, K)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	5	In PDB GlyTouCan (G42666HT)
5	L, M, N, O, P (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	5	Chemie (NAG)
6	Q, R, S, T (A, B, C, D)	water	water		18.0	1237	Chemie (HOH)

Sequence modifications

A, B: 33 - 766 (UniProt: P27487)

PDB	External Database	Details
His 767	-	expression tag
His 768	-	expression tag
His 769	-	expression tag
His 770	-	expression tag
His 771	-	expression tag
His 772	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	172443.0
Branched	Number of molecules	7
	Total formula weight	2856.7
Non-Polymers*	Number of molecules	5
	Total formula weight	1106.0
All*	Total formula weight	176405.7

*Water molecules are not included.