1W85
The crystal structure of pyruvate dehydrogenase E1 bound to the peripheral subunit binding domain of E2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G | PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT | polymer | 368 | 41387.0 | 4 | UniProt (P21873) Pfam (PF00676) In PDB | GEOBACILLUS STEAROTHERMOPHILUS | |
| 2 | B, D, F, H | PYRUVATE DEHYDROGENASE E1 COMPONENT, BETA SUBUNIT | polymer | 324 | 35364.4 | 4 | UniProt (P21874) Pfam (PF02779) Pfam (PF02780) In PDB | GEOBACILLUS STEAROTHERMOPHILUS | |
| 3 | I, J | DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE | polymer | 49 | 5262.1 | 2 | UniProt (P11961) Pfam (PF02817) In PDB | GEOBACILLUS STEAROTHERMOPHILUS | E2, DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX |
| 4 | A, B, C, E, F... | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
| 5 | A, C, G | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 6 | A, C, E, G | THIAMINE DIPHOSPHATE | non-polymer | 425.3 | 4 | Chemie (TPP) | |||
| 7 | H, B, D, F | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 8 | water | water | 18.0 | 1733 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 317529.9 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 2321.8 | |
| All* | Total formula weight | 319851.7 |
