1W7H

p38 Kinase crystal structure in complex with small molecule inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	MITOGEN-ACTIVATED PROTEIN KINASE 14	polymer	360	41343.2	1	UniProt (Q16539) Pfam (PF00069)	HOMO SAPIENS (HUMAN)	P38 MAP KINASE, MITOGEN-ACTIVATED PROTEIN KINASE P38 ALPHA, MAP KINASE P38ALPHA, CYTOKINE SUPPRESSIVE ANTI-INFLAMMATORY DRUG BINDING PROTEIN CSAID BINDING PROTEIN, CSBP, MAX-INTERACTING PROTEIN 2 MAP KINASE MXI2, SAPK2A
2	B (A)	3-(BENZYLOXY)PYRIDIN-2-AMINE	non-polymer		200.2	1	Chemie (3IP)
3	C (A)	water	water		18.0	468	Chemie (HOH)

Sequence modifications

A: 1 - 1 (PDB: 1W7H)
A: 2 - 360 (UniProt: Q16539)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	41343.2
Non-Polymers*	Number of molecules	1
	Total formula weight	200.2
All*	Total formula weight	41543.4

*Water molecules are not included.