1W6N
X-RAY CRYSTAL STRUCTURE OF C2S HUMAN GALECTIN-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GALECTIN-1 | polymer | 134 | 14657.4 | 1 | UniProt (P09382) Pfam (PF00337) | HOMO SAPIENS (HUMAN) | BETA-GALACTOSIDE-BINDING LECTIN L-14-I, HPL, LACTOSE-BINDING LECTIN 1, S-LAC LECTIN 1, GALAPTIN, HBL |
| 2 | B (B) | GALECTIN-1 | polymer | 134 | 14641.4 | 1 | UniProt (P09382) Pfam (PF00337) | HOMO SAPIENS (HUMAN) | BETA-GALACTOSIDE-BINDING LECTIN L-14-I, HPL, LACTOSE-BINDING LECTIN 1, S-LAC LECTIN 1, GALAPTIN, HBL |
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D, E, F, G, H (A, B) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 5 | Chemie (BME) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 218 | Chemie (HOH) |
Sequence modifications
A: 1001 - 1134 (UniProt: P09382)
B: 2001 - 2134 (UniProt: P09382)
| PDB | External Database | Details |
|---|---|---|
| Ser 1002 | Cys 2 | engineered mutation |
| Asp 1065 | Gly 65 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ser 2002 | Cys 2 | engineered mutation |
| Asp 2065 | Gly 65 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29298.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 486.7 | |
| All* | Total formula weight | 29785.6 |
