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1W6J

Structure of human OSC in complex with Ro 48-8071

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
LANOSTEROL SYNTHASEpolymer73283406.61UniProt (P48449)
Pfam (PF00432)
HOMO SAPIENS (HUMAN)OXIDOSQUALENE--LANOSTEROL CYCLASE, OXIDO SQUALENE CYCLASE, 2,3-EPOXYSQUALENE--LANOSTEROL CYCLASE, OSC
2B
(A)
[4-({6-[ALLYL(METHYL)AMINO]HEXYL}OXY)-2-FLUOROPHENYL](4-BROMOPHENYL)METHANONEnon-polymer448.41Chemie (R71)
3C, E, F
(A)
octyl beta-D-glucopyranosidenon-polymer292.43Chemie (BOG)
4D
(A)
TETRADECANEnon-polymer198.41Chemie (C14)
5G
(A)
waterwater18.0416Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight83406.6
Non-Polymers*Number of molecules5
Total formula weight1523.9
All*Total formula weight84930.5
*Water molecules are not included.

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PDB entries from 2025-12-10

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