1W6H

Novel plasmepsin II-inhibitor complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	PLASMEPSIN 2	polymer	331	37123.9	2	UniProt (P46925) Pfam (PF00026)	PLASMODIUM FALCIPARUM	ASPARTIC PROTEASE, ASPARTIC HEMOGLOBINASE II, PFAPD
2	C, D (A, B)	N-((3S,4S)-5-[(4-BROMOBENZYL)OXY]-3-HYDROXY-4-{[N-(PYRIDIN-2-YLCARBONYL)-L-VALYL]AMINO}PENTANOYL)-L-ALANYL-L-LEUCINAMIDE	non-polymer		705.6	2	Chemie (TIT)
3	E, F (A, B)	water	water		18.0	230	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	74247.9
Non-Polymers*	Number of molecules	2
	Total formula weight	1411.3
All*	Total formula weight	75659.2

*Water molecules are not included.