1W4R

Structure of a type II thymidine kinase with bound dTTP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	THYMIDINE KINASE	polymer	195	21788.4	8	UniProt (P04183) Pfam (PF00265)	HOMO SAPIENS (HUMAN)
2	I, K, M, O, Q... (A, B, C, D, E...)	THYMIDINE-5'-TRIPHOSPHATE	non-polymer		482.2	8	Chemie (TTP)
3	J, L, N, P, R... (A, B, C, D, E...)	ZINC ION	non-polymer		65.4	8	Chemie (ZN)
4	S (E)	(2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL	non-polymer		154.3	1	Chemie (DTU)
5	AA, BA, CA, DA, EA... (B, C, D, E, F...)	water	water		18.0	794	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 15 - 194 (UniProt: P04183)

PDB	External Database	Details
Met 0	-	expression tag
Arg 1	-	expression tag
Gly 2	-	expression tag
Ser 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
Leu 10	-	expression tag
Val 11	-	expression tag
Pro 12	-	expression tag
Arg 13	-	expression tag
Gly 14	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	174307.4
Non-Polymers*	Number of molecules	17
	Total formula weight	4534.9
All*	Total formula weight	178842.3

*Water molecules are not included.