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1W2D

Human Inositol (1,4,5)-trisphosphate 3-kinase complexed with Mn2+/ADP/Ins(1,3,4,5)P4

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BINOSITOL-TRISPHOSPHATE 3-KINASE Apolymer26530425.72UniProt (P23677)
Pfam (PF03770)
In PDB
HOMO SAPIENS (HUMAN)INOSITOL 1,4,5-TRISPHOSPHATE 3-KINASE, IP3-3K
2A, BADENOSINE-5'-DIPHOSPHATEnon-polymer427.22Chemie (ADP)
3A, BINOSITOL-(1,3,4,5)-TETRAKISPHOSPHATEnon-polymer500.12Chemie (4IP)
4A, BMANGANESE (II) IONnon-polymer54.92Chemie (MN)
5A, BSULFATE IONnon-polymer96.13Chemie (SO4)
6waterwater18.0259Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight60851.3
Non-Polymers*Number of molecules9
Total formula weight2252.6
All*Total formula weight63103.9
*Water molecules are not included.

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PDB entries from 2024-07-24

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