1W22
Crystal structure of inhibited human HDAC8
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HISTONE DEACETYLASE 8 | polymer | 377 | 41802.5 | 2 | UniProt (Q9BY41) Pfam (PF00850) | HOMO SAPIENS | HDAC8, HD8, CDA07 |
| 2 | C, G (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, E, H, I (A, B) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 4 | F, J (A, B) | N-HYDROXY-4-(METHYL{[5-(2-PYRIDINYL)-2-THIENYL]SULFONYL}AMINO)BENZAMIDE | non-polymer | 389.4 | 2 | Chemie (NHB) | |||
| 5 | K, L (A, B) | water | water | 18.0 | 280 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 83605.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1066.1 | |
| All* | Total formula weight | 84671.1 |
