1W0G

Crystal structure of human cytochrome P450 3A4

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	CYTOCHROME P450 3A4	polymer	485	55481.5	1	UniProt (P08684) Pfam (PF00067) In PDB	HOMO SAPIENS (HUMAN)	QUININE 3-MONOOXYGENASE, CYPIIIA4, NIFEDIPINE OXIDASE, NF-25, P450-PCN1
2	A	METYRAPONE	non-polymer		226.3	1	Chemie (MYT)
3	A	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	1	Chemie (HEM)
4		water	water		18.0	29	Chemie (HOH)

Sequence modifications

A: 23 - 24 (PDB: 1W0G)
A: 504 - 507 (PDB: 1W0G)
A: 25 - 503 (UniProt: P08684)

PDB	External Database	Details
Val 392	Trp 391	conflict

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	55481.5
Non-Polymers*	Number of molecules	2
	Total formula weight	842.8
All*	Total formula weight	56324.2

*Water molecules are not included.