1W0E
Crystal structure of human cytochrome P450 3A4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CYTOCHROME P450 3A4 | polymer | 485 | 55481.5 | 1 | UniProt (P08684) Pfam (PF00067) | HOMO SAPIENS (HUMAN) | QUININE 3-MONOOXYGENASE, CYPIIIA4, NIFEDIPINE OXIDASE, NF-25, P450-PCN1 |
| 2 | B (A) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 3 | C (A) | water | water | 18.0 | 28 | Chemie (HOH) |
Sequence modifications
A: 23 - 24 (PDB: 1W0E)
A: 504 - 507 (PDB: 1W0E)
A: 25 - 503 (UniProt: P08684)
A: 504 - 507 (PDB: 1W0E)
A: 25 - 503 (UniProt: P08684)
| PDB | External Database | Details |
|---|---|---|
| Val 392 | Trp 391 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 55481.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 616.5 | |
| All* | Total formula weight | 56098.0 |
