1VZX
Roles of active site tryptophans in substrate binding and catalysis by ALPHA-1,3 GALACTOSYLTRANSFERASE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE | polymer | 289 | 34067.1 | 2 | UniProt (P14769) Pfam (PF03414) | BOS TAURUS (BOVINE) | GALACTOSYLTRANSFERASE, UDP-GALACTOSE, BETA-D-GALACTOSYL-1,4-N-ACETYL-D-GLUCOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE |
| 2 | C, D (C, D) | beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 383.3 | 2 | In PDB GlyTouCan (G00055MO) | |||
| 3 | E, H (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) PubChem (27854) | |||
| 4 | F, I (A, B) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 2 | Chemie (UDP) PubChem (1158) PubChem (6031) PubChem (25323044) PubChem (25323048) PubChem (44298965) PubChem (53486216) PubChem (3084486) PubChem (60098857) PubChem (57448939) PubChem (6101632) PubChem (6604175) PubChem (91746160) PubChem (92332560) PubChem (92332561) PubChem (92332562) PubChem (92332563) PubChem (11811538) PubChem (93088131) PubChem (93630083) PubChem (12049241) | |||
| 5 | G, J (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) PubChem (753) | |||
| 6 | K, L (A, B) | water | water | 18.0 | 642 | Chemie (HOH) |
Sequence modifications
A, B: 80 - 368 (UniProt: P14769)
| PDB | External Database | Details |
|---|---|---|
| Tyr 314 | Trp 314 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68134.3 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 766.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1102.4 | |
| All* | Total formula weight | 70003.3 |
