1VZE
L. CASEI THYMIDYLATE SYNTHASE MUTANT E60Q TERNARY COMPLEX WITH DUMP AND CB3717
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | THYMIDYLATE SYNTHASE | polymer | 316 | 36585.5 | 1 | UniProt (P00469) Pfam (PF00303) | Lactobacillus casei | TS, LCTS |
| 2 | B (A) | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE | non-polymer | 308.2 | 1 | Chemie (UMP) | |||
| 3 | C (A) | 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID | non-polymer | 477.5 | 1 | Chemie (CB3) | |||
| 4 | D (A) | water | water | 18.0 | 238 | Chemie (HOH) |
Sequence modifications
A: 1 - 316 (UniProt: P00469)
| PDB | External Database | Details |
|---|---|---|
| Gln 60 | Glu 60 | engineered mutation |
| Ala 111 | Asp 111 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36585.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 785.7 | |
| All* | Total formula weight | 37371.1 |
