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1VZA

THYMIDYLATE SYNTHASE E60D MUTANT BINARY COMPLEX WITH 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
THYMIDYLATE SYNTHASEpolymer31636572.41UniProt (P00469)
Pfam (PF00303)
Lactobacillus caseiTS, LCTS
2B
(A)
2'-DEOXYURIDINE 5'-MONOPHOSPHATEnon-polymer308.21Chemie (UMP)
3C
(A)
waterwater18.029Chemie (HOH)
Sequence modifications
A: 1 - 316 (UniProt: P00469)
PDBExternal DatabaseDetails
Asp 60Glu 60engineered mutation
Ala 111Asp 111conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight36572.4
Non-Polymers*Number of molecules1
Total formula weight308.2
All*Total formula weight36880.6
*Water molecules are not included.

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PDB entries from 2025-06-18

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