1VR1
Specifity for Plasminogen Activator Inhibitor-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | thrombin | polymer | 27 | 3188.6 | 1 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (human) | Coagulation factor II |
| 2 | B (H) | thrombin | polymer | 261 | 30186.7 | 1 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (human) | Coagulation factor II |
| 3 | C (I) | Hirudin | polymer | 10 | 1363.4 | 1 | UniProt (P28504) UniProt (by SIFTS) (P01050) | Hirudo medicinalis (Medicinal leech) | |
| 4 | D, E, F (L, H, I) | water | water | 18.0 | 81 | Chemie (HOH) |
Sequence modifications
H: 16 - 245 (UniProt: P00734)
| PDB | External Database | Details |
|---|---|---|
| Ala 35 | - | conflict |
| Lys 36 | - | conflict |
| His 37 | - | conflict |
| Arg 37 | Lys 384 | conflict |
| Gly 37 | Gln 387 | conflict |
| Arg 39 | - | conflict |
| Phe 40 | Leu 389 | conflict |
| Tyr 184 | Gly 552 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 34738.8 | |
| All* | Total formula weight | 34738.8 |
