1V2K
Factor XA specific Inhibitor in complex with bovine trypsin variant X(triple.Glu)bT.D2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | T | Trypsin | polymer | 223 | 23404.4 | 1 | UniProt (P00760) Pfam (PF00089) In PDB | Bos taurus (cattle) | Beta-trypsin |
2 | T | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
3 | T | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
4 | T | [4-(6-CHLORO-NAPHTHALENE-2-SULFONYL)-PIPERAZIN-1-YL]- (3,4,5,6-TETRAHYDRO-2H-[1,4']BIPYRIDINYL-4-YL)- METHANONE | non-polymer | 499.0 | 1 | Chemie (ZEN) | |||
5 | water | water | 18.0 | 95 | Chemie (HOH) |
Sequence modifications
T: 16 - 245 (UniProt: P00760)
PDB | External Database | Details |
---|---|---|
Glu 97 | Asn 99 | engineered mutation |
Tyr 99 | Leu 101 | engineered mutation |
Ser 172 | Tyr 172 | engineered mutation |
Ser 173 | Pro 173 | engineered mutation |
Phe 174 | Gly 174 | engineered mutation |
Ile 175 | Gln 175 | engineered mutation |
Ala 190 | Ser 192 | engineered mutation |
Glu 217 | Ser 215 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 23404.4 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 635.2 | |
All* | Total formula weight | 24039.5 |