1UXI
Large improvement in the thermal stability of a tetrameric malate dehydrogenase by single point mutations at the dimer-dimer interface
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | MALATE DEHYDROGENASE | polymer | 309 | 32747.8 | 2 | UniProt (P80040) Pfam (PF00056) Pfam (PF02866) In PDB | CHLOROFLEXUS AURANTIACUS | |
| 2 | A, B | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
| 3 | A, B | FUMARIC ACID | non-polymer | 116.1 | 2 | Chemie (FUM) | |||
| 4 | B | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | water | water | 18.0 | 450 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 309 (UniProt: P80040)
| PDB | External Database | Details |
|---|---|---|
| Lys 165 | Glu 165 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65495.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1582.0 | |
| All* | Total formula weight | 67077.6 |
