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1UOU

Crystal structure of human thymidine phosphorylase in complex with a small molecule inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ATHYMIDINE PHOSPHORYLASEpolymer47449195.41UniProt (P19971)
Pfam (PF02885)
Pfam (PF00591)
Pfam (PF07831)
In PDB
HOMO SAPIENS (HUMAN)TDRPASE, TP, PLATELET-DERIVED ENDOTHELIAL CELL GROWTH FACTOR, PD-ECGF, GLIOSTATIN
2A5-CHLORO-6-(1-(2-IMINOPYRROLIDINYL) METHYL) URACILnon-polymer242.71Chemie (CMU)
3waterwater18.075Chemie (HOH)
Sequence modifications
A: 7 - 11 (PDB: 1UOU)
A: 12 - 408 (UniProt: P19971)
A: 411 - 482 (UniProt: P19971)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight49195.4
Non-Polymers*Number of molecules1
Total formula weight242.7
All*Total formula weight49438.0
*Water molecules are not included.

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PDB entries from 2024-10-02

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