1UOU
Crystal structure of human thymidine phosphorylase in complex with a small molecule inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | THYMIDINE PHOSPHORYLASE | polymer | 474 | 49195.4 | 1 | UniProt (P19971) Pfam (PF02885) Pfam (PF00591) Pfam (PF07831) | HOMO SAPIENS (HUMAN) | TDRPASE, TP, PLATELET-DERIVED ENDOTHELIAL CELL GROWTH FACTOR, PD-ECGF, GLIOSTATIN |
| 2 | B (A) | 5-CHLORO-6-(1-(2-IMINOPYRROLIDINYL) METHYL) URACIL | non-polymer | 242.7 | 1 | Chemie (CMU) | |||
| 3 | C (A) | water | water | 18.0 | 75 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 49195.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 242.7 | |
| All* | Total formula weight | 49438.0 |
