1UHO
Crystal structure of Human Phosphodiesterase 5 complexed with Vardenafil(Levitra)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | cGMP-specific 3',5'-cyclic phosphodiesterase | polymer | 324 | 37530.3 | 1 | UniProt (O76074) Pfam (PF00233) | Homo sapiens (human) | PDE5, Phosphodiesterase 5 |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | 2-{2-ETHOXY-5-[(4-ETHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-5-METHYL-7-PROPYLIMIDAZO[5,1-F][1,2,4]TRIAZIN-4(1H)-ONE | non-polymer | 488.6 | 1 | Chemie (VDN) | |||
| 5 | E (A) | water | water | 18.0 | 116 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37530.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 578.3 | |
| All* | Total formula weight | 38108.6 |
