1UCN
X-ray structure of human nucleoside diphosphate kinase A complexed with ADP at 2 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | nucleoside diphosphate kinase A | polymer | 152 | 17128.7 | 3 | UniProt (P15531) Pfam (PF00334) | Homo sapiens (human) | |
| 2 | D, G, L (A, B, C) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 3 | E, H, I, M, N (A, B, C) | CALCIUM ION | non-polymer | 40.1 | 5 | Chemie (CA) | |||
| 4 | F, J, O (A, B, C) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 3 | Chemie (ADP) | |||
| 5 | K (B) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 6 | P, Q, R (A, B, C) | water | water | 18.0 | 336 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 152 (UniProt: P15531)
| PDB | External Database | Details |
|---|---|---|
| Trp 60 | Phe 60 | engineered mutation |
| Gly 118 | His 118 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 51386.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1889.0 | |
| All* | Total formula weight | 53275.0 |
