1U5R

Crystal Structure of the TAO2 Kinase Domain: Activation and Specifity of a Ste20p MAP3K

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	serine/threonine protein kinase TAO2	polymer	348	39910.5	2	UniProt (Q9JLS3) Pfam (PF00069)	Rattus norvegicus (Norway rat)
2	C, D, G, H (A, B)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
3	E, I (A, B)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
4	F, J (A, B)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	2	Chemie (ATP)
5	K, L (A, B)	water	water		18.0	383	Chemie (HOH)

Sequence modifications

A, B: 1 - 320 (UniProt: Q9JLS3)

PDB	External Database	Details
Met -27	-	cloning artifact
Ser -26	-	cloning artifact
Tyr -25	-	cloning artifact
Tyr -24	-	cloning artifact
His -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
Asp -17	-	cloning artifact
Tyr -16	-	cloning artifact
Asp -15	-	cloning artifact
Ile -14	-	cloning artifact
Pro -13	-	cloning artifact
Thr -12	-	cloning artifact
Thr -11	-	cloning artifact
Glu -10	-	cloning artifact
Asn -9	-	cloning artifact
Leu -8	-	cloning artifact
Tyr -7	-	cloning artifact
Phe -6	-	cloning artifact
Gln -5	-	cloning artifact
Gly -4	-	cloning artifact
Ala -3	-	cloning artifact
Met -2	-	cloning artifact
Asp -1	-	cloning artifact
Pro 0	-	cloning artifact
Sep 181	Ser 181	modified residue

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	79820.9
Non-Polymers*	Number of molecules	8
	Total formula weight	1191.7
All*	Total formula weight	81012.7

*Water molecules are not included.