1U54
Crystal Structures of the Phosphorylated and Unphosphorylated Kinase Domains of the CDC42-associated Tyrosine Kinase ACK1 bound to AMP-PCP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Activated CDC42 kinase 1 | polymer | 291 | 33138.0 | 1 | UniProt (Q07912) Pfam (PF07714) In PDB | Homo sapiens (human) | ACK-1 |
| 2 | B | Activated CDC42 kinase 1 | polymer | 291 | 33058.0 | 1 | UniProt (Q07912) Pfam (PF07714) In PDB | Homo sapiens (human) | ACK-1 |
| 3 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | A, B | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | non-polymer | 505.2 | 2 | Chemie (ACP) | |||
| 5 | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence modifications
A: 109 - 395 (UniProt: Q07912)
B: 109 - 395 (UniProt: Q07912)
| PDB | External Database | Details |
|---|---|---|
| Gly 107 | - | cloning artifact |
| Ser 108 | - | cloning artifact |
| Ptr 284 | Tyr 284 | modified residue |
| Glu 396 | - | cloning artifact |
| Phe 397 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 107 | - | cloning artifact |
| Ser 108 | - | cloning artifact |
| Glu 396 | - | cloning artifact |
| Phe 397 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66196.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1107.6 | |
| All* | Total formula weight | 67303.7 |
