1U4D
Structure of the ACK1 Kinase Domain bound to Debromohymenialdisine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Activated CDC42 kinase 1 | polymer | 291 | 33058.0 | 2 | UniProt (Q07912) Pfam (PF07714) | Homo sapiens (human) | ACK-1 |
| 2 | C, E (A, B) | DEBROMOHYMENIALDISINE | non-polymer | 245.2 | 2 | Chemie (DBQ) | |||
| 3 | D (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 157 | Chemie (HOH) |
Sequence modifications
A, B: 109 - 395 (UniProt: Q07912)
| PDB | External Database | Details |
|---|---|---|
| Gly 107 | - | cloning artifact |
| Ser 108 | - | cloning artifact |
| Glu 396 | - | cloning artifact |
| Phe 397 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66116.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 525.9 | |
| All* | Total formula weight | 66642.0 |
