1TZS
Crystal Structure of an activation intermediate of Cathepsin E
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Cathepsin E | polymer | 351 | 37663.9 | 1 | UniProt (P14091) Pfam (PF00026) In PDB | Homo sapiens (human) | |
2 | P | activation peptide from Cathepsin E | polymer | 35 | 4222.0 | 1 | UniProt (P14091) Pfam (PF07966) In PDB | Homo sapiens (human) | |
3 | X | 23-mer peptide from PelB-IgG kappa light chain fusion protein | polymer | 23 | 2361.0 | 1 | GenBank (5834246) | ||
4 | water | water | 18.0 | 214 | Chemie (HOH) |
Sequence modifications
A: 1 - 343 (UniProt: P14091)
X: 1 - 22 (GenBank: 5834246)
PDB | External Database | Details |
---|---|---|
- | Ala 155 | SEE REMARK 999 |
- | Phe 156 | SEE REMARK 999 |
- | Ala 157 | SEE REMARK 999 |
- | Thr 158 | SEE REMARK 999 |
- | Gln 159 | SEE REMARK 999 |
Trp 344 | - | cloning artifact |
Ser 345 | - | cloning artifact |
His 346 | - | cloning artifact |
Pro 347 | - | cloning artifact |
Gln 348 | - | cloning artifact |
Phe 349 | - | cloning artifact |
Glu 350 | - | cloning artifact |
Lys 351 | - | cloning artifact |
PDB | External Database | Details |
---|---|---|
Met 23 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 44246.8 | |
All* | Total formula weight | 44246.8 |