1TZS
Crystal Structure of an activation intermediate of Cathepsin E
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cathepsin E | polymer | 351 | 37663.9 | 1 | UniProt (P14091) Pfam (PF00026) | Homo sapiens (human) | |
| 2 | B (P) | activation peptide from Cathepsin E | polymer | 35 | 4222.0 | 1 | UniProt (P14091) Pfam (PF07966) | Homo sapiens (human) | |
| 3 | C (X) | 23-mer peptide from PelB-IgG kappa light chain fusion protein | polymer | 23 | 2361.0 | 1 | GenBank (5834246) | ||
| 4 | D, E, F (A, P, X) | water | water | 18.0 | 214 | Chemie (HOH) |
Sequence modifications
A: 1 - 343 (UniProt: P14091)
X: 1 - 22 (GenBank: 5834246)
| PDB | External Database | Details |
|---|---|---|
| - | Ala 155 | SEE REMARK 999 |
| - | Phe 156 | SEE REMARK 999 |
| - | Ala 157 | SEE REMARK 999 |
| - | Thr 158 | SEE REMARK 999 |
| - | Gln 159 | SEE REMARK 999 |
| Trp 344 | - | cloning artifact |
| Ser 345 | - | cloning artifact |
| His 346 | - | cloning artifact |
| Pro 347 | - | cloning artifact |
| Gln 348 | - | cloning artifact |
| Phe 349 | - | cloning artifact |
| Glu 350 | - | cloning artifact |
| Lys 351 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Met 23 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 44246.8 | |
| All* | Total formula weight | 44246.8 |
