1TU6

Cathepsin K complexed with a ketoamide inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Cathepsin K	polymer	215	23523.5	2	UniProt (P43235) Pfam (PF00112)	Homo sapiens (human)	Cathepsin O, Cathepsin X, Cathepsin O2
2	C, D, F (A, B)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
3	E, G (A, B)	[1-(4-FLUOROBENZYL)CYCLOBUTYL]METHYL (1S)-1-[OXO(1H-PYRAZOL-5-YLAMINO)ACETYL]PENTYLCARBAMATE	non-polymer		444.5	2	Chemie (FSP)
4	H, I (A, B)	water	water		18.0	371	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	47047.0
Non-Polymers*	Number of molecules	5
	Total formula weight	1177.2
All*	Total formula weight	48224.1

*Water molecules are not included.