1TMU
Changes in interactions in complexes of hirudin derivatives and human alpha-thrombin due to different crystal forms
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | L | Thrombin light chain | polymer | 28 | 3317.7 | 1 | UniProt (P00734) Pfam (PF09396) In PDB | Homo sapiens (human) | Coagulation factor II |
2 | H | Thrombin heavy chain | polymer | 259 | 29780.2 | 1 | UniProt (P00734) Pfam (PF00089) In PDB | Homo sapiens (human) | Coagulation factor II |
3 | J | Hirudin variant-2 | polymer | 11 | 1491.5 | 1 | UniProt (P09945) In PDB | HIRUDO MEDICINALIS | |
4 | H | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide | non-polymer | 454.0 | 1 | BIRD (PRD_000020) Chemie (0G6) | |||
5 | H | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
6 | water | water | 18.0 | 72 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 34589.5 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 675.2 | |
All* | Total formula weight | 35264.7 |