1TLC

THYMIDYLATE SYNTHASE COMPLEXED WITH DGMP AND FOLATE ANALOG 1843U89

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	THYMIDYLATE SYNTHASE	polymer	265	30543.7	2	UniProt (P00470) Pfam (PF00303) UniProt (by SIFTS) (P0A884)	Escherichia coli
2	C, E (A, B)	2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE	non-polymer		347.2	2	Chemie (DGP)
3	D, F (A, B)	S)-2-(5(((1,2-DIHYDRO-3-METHYL-1-OXOBENZO(F)QUINAZOLIN-9-YL)METHYL)AMINO)1-OXO-2-ISOINDOLINYL)GLUTARIC ACID	non-polymer		500.5	2	Chemie (F89)
4	G, H (A, B)	water	water		18.0	166	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	61087.3
Non-Polymers*	Number of molecules	4
	Total formula weight	1695.4
All*	Total formula weight	62782.8

*Water molecules are not included.