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1TKZ

CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH GW429576

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Pol polyprotein, Reverse transcriptase, Chain Apolymer56064594.91UniProt (P04585)
Pfam (PF00078)
Pfam (PF06817)
Pfam (PF06815)
Pfam (PF00075)
Human immunodeficiency virus 1
2B
(B)
Pol polyprotein, Reverse transcriptase, Chain Bpolymer44051399.01UniProt (P04585)
Pfam (PF00078)
Pfam (PF06817)
Pfam (PF06815)
Human immunodeficiency virus 1
3C, D, E
(A)
PHOSPHATE IONnon-polymer95.03Chemie (PO4)
4F
(A)
6-CHLORO-4-(CYCLOHEXYLSULFANYL)-3-PROPYLQUINOLIN-2(1H)-ONEnon-polymer335.91Chemie (H16)
Sequence modifications
A: 1 - 560 (UniProt: P04585)
PDBExternal DatabaseDetails
Csd 280Cys 435modified residue
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight115994.0
Non-Polymers*Number of molecules4
Total formula weight620.8
All*Total formula weight116614.8
*Water molecules are not included.

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PDB entries from 2025-06-18

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