1TKT
CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH GW426318
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Pol polyproteins [Reverse transcriptase], Chain A | polymer | 560 | 64594.9 | 1 | UniProt (P04585) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) | Human immunodeficiency virus 1 | |
| 2 | B (B) | Pol polyproteins [Reverse transcriptase], Chain B | polymer | 440 | 51399.0 | 1 | UniProt (P04585) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) | Human immunodeficiency virus 1 | |
| 3 | C, D, E (A) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 4 | F (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | G (A) | 6-CHLORO-4-(CYCLOHEXYLOXY)-3-PROPYLQUINOLIN-2(1H)-ONE | non-polymer | 319.8 | 1 | Chemie (H12) | |||
| 6 | H, I (A, B) | water | water | 18.0 | 37 | Chemie (HOH) |
Sequence modifications
A: 1 - 560 (UniProt: P04585)
| PDB | External Database | Details |
|---|---|---|
| Csd 280 | Cys 435 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 115994.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 629.0 | |
| All* | Total formula weight | 116623.0 |
