1TKB

SPECIFICITY OF COENZYME BINDING IN THIAMIN DIPHOSPHATE DEPENDENT ENZYMES: CRYSTAL STRUCTURES OF YEAST TRANSKETOLASE IN COMPLEX WITH ANALOGS OF THIAMIN DIPHOSPHATE

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	TRANSKETOLASE	polymer	678	73655.1	2	UniProt (P23254) Pfam (PF00456) Pfam (PF02779) Pfam (PF02780)	Saccharomyces cerevisiae (baker's yeast)
2	C, E (A, B)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
3	D, F (A, B)	1'-DEAZO-THIAMIN DIPHOSPHATE	non-polymer		423.3	2	Chemie (N1T)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	147310.2
Non-Polymers*	Number of molecules	4
	Total formula weight	926.8
All*	Total formula weight	148237.0

*Water molecules are not included.